Chapter 4. Modelling Tel-AML1 oncogenic translocation using knockin mice and transposon-mediated insertional mutagenesis
![Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia | Oncogene Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia | Oncogene](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fsj.onc.1207672/MediaObjects/41388_2004_Article_BF1207672_Fig2_HTML.jpg)
Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia | Oncogene
![TEL-AML1 antibody design and specificity testing. (a) Design strategy... | Download Scientific Diagram TEL-AML1 antibody design and specificity testing. (a) Design strategy... | Download Scientific Diagram](https://www.researchgate.net/profile/Pablo-Landgraf/publication/257754028/figure/fig3/AS:267755236622348@1440849231566/TEL-AML1-antibody-design-and-specificity-testing-a-Design-strategy-for-the-TEL-AML1.png)
TEL-AML1 antibody design and specificity testing. (a) Design strategy... | Download Scientific Diagram
![Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study | Journal of Hematology & Oncology | Full Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study | Journal of Hematology & Oncology | Full](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2F1756-8722-1-17/MediaObjects/13045_2008_Article_17_Fig1_HTML.jpg)
Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study | Journal of Hematology & Oncology | Full
![JCI - The TEL-AML1 leukemia fusion gene dysregulates the TGF-β pathway in early B lineage progenitor cells JCI - The TEL-AML1 leukemia fusion gene dysregulates the TGF-β pathway in early B lineage progenitor cells](https://dm5migu4zj3pb.cloudfront.net/manuscripts/36000/36428/medium/JCI36428.f5.jpg)
JCI - The TEL-AML1 leukemia fusion gene dysregulates the TGF-β pathway in early B lineage progenitor cells
![The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation | Oncogene The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation | Oncogene](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fonc.2015.50/MediaObjects/41388_2015_Article_BFonc201550_Fig3_HTML.jpg)
The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation | Oncogene
![Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study | Journal of Hematology & Oncology | Full Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study | Journal of Hematology & Oncology | Full](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2F1756-8722-1-17/MediaObjects/13045_2008_Article_17_Fig2_HTML.jpg)
Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study | Journal of Hematology & Oncology | Full
![Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia | Oncogene Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia | Oncogene](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fsj.onc.1207672/MediaObjects/41388_2004_Article_BF1207672_Fig5_HTML.jpg)
Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia | Oncogene
![TEL/AML-1 Dimerizes and Is Associated With a Favorable Outcome in Childhood Acute Lymphoblastic Leukemia - ScienceDirect TEL/AML-1 Dimerizes and Is Associated With a Favorable Outcome in Childhood Acute Lymphoblastic Leukemia - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0006497120611703-gr2.jpg)
TEL/AML-1 Dimerizes and Is Associated With a Favorable Outcome in Childhood Acute Lymphoblastic Leukemia - ScienceDirect
![Case 1: interphase FISH using dual-color TEL/AML1 translocation probe,... | Download Scientific Diagram Case 1: interphase FISH using dual-color TEL/AML1 translocation probe,... | Download Scientific Diagram](https://www.researchgate.net/publication/11829726/figure/fig1/AS:280193567608870@1443814760700/Case-1-interphase-FISH-using-dual-color-TEL-AML1-translocation-probe-showing-TEL-AML1.png)
Case 1: interphase FISH using dual-color TEL/AML1 translocation probe,... | Download Scientific Diagram
![Detection of TEL/AML1 translocation in cord blood cells. Cells stained... | Download Scientific Diagram Detection of TEL/AML1 translocation in cord blood cells. Cells stained... | Download Scientific Diagram](https://www.researchgate.net/profile/Arthur-Zelent/publication/8550537/figure/fig1/AS:280996432891906@1444006178597/A-schematic-representation-of-the-full-length-AML1-TEL-and-TEL-AML1-proteins-The-RUNT_Q320.jpg)
Detection of TEL/AML1 translocation in cord blood cells. Cells stained... | Download Scientific Diagram
![FISH analysis of TEL-AML1 fusion and TEL deletion. Representative cells... | Download Scientific Diagram FISH analysis of TEL-AML1 fusion and TEL deletion. Representative cells... | Download Scientific Diagram](https://www.researchgate.net/publication/11906263/figure/fig3/AS:282072313810952@1444262688676/FISH-analysis-of-TEL-AML1-fusion-and-TEL-deletion-Representative-cells-from-T1-2.png)
FISH analysis of TEL-AML1 fusion and TEL deletion. Representative cells... | Download Scientific Diagram
![Secondary Somatic Mutations in ETV6-RUNX1 Acute Lymphoblastic Leukemia Pathogenesis | Semantic Scholar Secondary Somatic Mutations in ETV6-RUNX1 Acute Lymphoblastic Leukemia Pathogenesis | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/a3e9eac8521a87604a301d6d22b85bc309727553/19-Figure3-1.png)